Entourage Effect


The “Entourage Effect” is a term coined by Shimon Ben-Shabat and Raphael Mechoulam back in 1998, to represent the biological synergy of cannabinoids, flavonoids and terpenes found in cannabis. When consuming cannabis flower, the cannabinoids and terpenes form a synergistic influence that changes and enhances the medical effect. This symbiosis between cannabinoids and terpenes is what gives different cultivars of cannabis their varied effects. Terpenes can do many things: they can improve the absorption of cannabinoids, overcome bacterial defense mechanisms, and even minimize side effects of high THC dosages.



Human interaction with cannabis as a medicinal plant stretches well beyond recorded history. It is only in the past half century that the components of medicinal cannabis efficacy have been studied.



The cannabis plant consists of a wide variety of chemicals and compounds. About 140 of these belong to a large class of organic hydrocarbons known as terpenes. Terpenes, unlike cannabinoids, are responsible for the aroma of cannabis.


Harmony Cultivars